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1.

Why am I childless? What is infertility/subfertility?

Infertility/Subfertility is a condition when a woman after one year of unprotected sexual intercourse not being able to conceive on her own. Both the partners need to be investigated together to treat this problem.
2.

Who needs to visit an Infertility Specialist?

When there is no conception after one year of unprotected intercourse in women of < 35 years, the couple should seek advice from Infertility specialist. When the woman is >38 years, they should seek advice after 6 months of unprotected intercourse.
3.

How common is infertility/subfertility?

It is known that 84% of women would conceive within one year of marriage; 92% in two years and 93% in after three years. It means some 5-15% of the married couples are facing this problem at any given time in a society.
4.

Is infertility becoming more common nowadays?

Though it may appear to be so, nevertheless, as people have become knowledgeable, more and more patients start approaching specialists to find out the cause of their subfertility status sooner than before. Notwithstanding that, there seems to be subtle decrease in our fertility rates as a society, thanks to our changed lifestyle, career needs and economic factors.
5.

What is a normal semen analysis?

Normally a man has about 40 to 100 million sperms in semen per ml. WHO has reported that 20 million sperms per ml with 50% motility as the requirement for natural conception to occur. Anybody whose count is consistently lower than this may require ART procedures.
6.

What are the pre-screening tests a couple with infertility problem need to undergo and why so many?

In order to investigate and analyze your infertility problem, we need to know the underlying medical problem which will help you to choose the correct option of treatment. for eg a semen analysis showing very few sperms will obviously direct the couple to ICSI without wasting any time. We accept reports from any reputed clinical laboratory for tests done within 6 months to one year. We generally prefer to do a simple semen analysis in our laboratory. One Semen analysis may not give the real status. If a person had a fever of more than 101’F for some days, he might expect to have a worse semen report for the next 3 months.
7.

Female Screening Requirements:

Blood Tests Day 2-4 (of un-medicated cycle) FSH, LH and estradiol levels
Rubella Antibody titre
HIV I and II
Chlamydia IgM/IgG status
Hepatitis B surface antigen HBsAg
Hemoglobin
Testosterone in some women
DHEASO4 in some women
Day 21 Progesterone to know the luteal functioning
Pelvic ultrasound to rule out ovarian cysts, fibroids, polyps and hydrosalpinges (fluid filled tubes)
Hysterosalpingogram (HSG) or hysteroscopy to evaluate uterine cavity and tubal patency
Male Screening Requirements:
Semen Analysis
HIV I and II
Hepatitis B surface antigen
VDRL
8.

What is a day 2 FSH and estradiol level and why should it be done only at that time?

These tests measure the level of follicle stimulating hormone (FSH) and estrogen on the second day of your menses period. The test values give us an indication of ‘ovarian reserve', in other words, how hard your pituitary gland in your brain has to work to stimulate your ovaries to ovulate. These values give us a rough idea to determine what IVF protocol to choose, how much hormone injection (FSH dose) may be required for stimulation and an insight into the potential success rates of IVF. Some centres may not accept a woman if her blood FSH level is > 11 mIU/mL.
9.

Why does this IVF treatment take so long?

As you may be aware, certain part of your brain (pituitary gland) controls your ovaries. If we have to bring your ovaries into our control for controlled stimulation, we need to delink your brain-ovary control axis and this is called down-regulation or ovarian suppression. You don’t panic, once you are off the medication, your brain will take over and your cycles will be restored as before.

This takes about 8 to 10 days in the cycle before the start of ovarian stimulation drugs. Soon after you get your proper menses, ovarian stimulation in the form of daily FSH injections is initiated and this lasts for about 9 to 14 days. Egg Collection is fixed in the next 2 days after giving you a shot of hCG injection for final maturation of your eggs. Embryo Transfer is fixed in the next 2 days following your egg collection. Basically the IVF treatment gets over by the time of Embryo Transfer. One has to wait for the result of pregnancy in the next 14 days. Actual treatment commences from the 21 st of the preceding menses cycle and lasts till about 14 to 16 day of IVF treatment cycle. Refer to our Typical IVF Calendar in Genesis.
10.

Is it possible for a woman without getting menses to conceive on her own?

Yes, in certain circumstances like polycystic ovarian disease where the anovulation is occurring due to hormonal imbalance. If we can make these ovulate with treatment, they have good chances of conceiving. If the problem is of premature menopause, she could get pregnant with donated eggs.
 
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